Acute kidney injury (AKI) represents a significant challenge in clinical practice. AKI is avoidable but when it develops, astute management and intervention on the part of the whole multidisciplinary team ensures that further insult to kidney function is minimised. Understanding the challenges in managing AKI requires an awareness of the historical background to AKI. Chapter 1 in this handbook provides an overview of the evolution of Acute Renal Failure to the now internationally agreed definition of AKI. The difficulties which clinicians encountered in managing AKI were not helped by the multiple definitions of what actually constituted AKI and how it could be staged. The development of a consensus on a definition of AKI as well as the establishment of the AKI staging framework – RIFLE (Risk, Injury, Failure, Loss of kidney function, and End-stage renal failure) has improved the clinical management of patients.


Education & Training - this is the Core of the Association. Development of Educational materials, organize educational events like the annual International Conference and several Seminars along Europe. The aim of the Association is to provide tools and knowledge to Healthcare professionals as well as our Patients.